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MY CARTNeem
AZADIRACHTA INDICA
Family: Meliaceae
Genus: Azadirachta
Common name: Neem, Indian lilac, Margosa
The health benefits of neem are multiple but what can be the secret behind Neem benefits?
As in other herbs, Neem beneficial effects are given by some of its active constituents, some of which the pharmaceutical industry have used as their primary source to build drugs against illnesses as important as cancer, for which already more than 400 active constituents derived from plants and herbs are used.
Herbs as Neem and Ginkgo biloba as well as many other well renown herbs have been in the scope of pharmaceutical companies since long ago, mainly due to the properties and health benefits exerted by some of their active constituents are known to act as health boosters.
More than 140 compounds have been isolated from different parts of Melia herb or neem. All parts of the neem tree as:
- leaves,
- flowers,
- seeds,
- fruits,
- roots and
- bark
have been used traditionally for the treatment of inflammation, infections, fever, skin diseases and dental disorders.
Among those active constituents, Neem has thirty-one nortriterpenoids, including 28 limonoids and 3 degraded limonoids, and one diterpenoid as well as azadirachtin.
Among all the properties and health benefits exerted by Azadirachta indica (Neem) we shall highlight one, its ability to treat skin and skin related problems, either as part of poly herbal anti-acne face wash gels formulations or part of anti-microbial preparations against some groups of bacteria.
Azadirachta indica (Neem) by itself doesn't seem to be much different from any other plant from its family and genus, but when we look closer we find some major differences that may indicate why this plant is so different, its active constituents, among which we find thirty-one nortriterpenoids, including 28 limonoids
At least one study reported how five of those active constituents found in Melia herb or Azadirachta indica (Neem) showed an important inhibitory effect on the melanogenesis in the B16 melanoma cells, with results of 74 to 91% reduction of melanin content at 25 micro G/ml and almost no toxicity to healthy cells[3], with which Neem becomes one of these plants to be noted for the development of new drugs based on the active constituents of this plant.
Neem leaves are responsible for some already mentioned neem benefits, they are known to possess immunomodulatory, anti-inflammatory, antihyperglycaemic, antiulcer, antimalarial, antifungal, antibacterial, antiviral, antioxidant, antimutagenic and anticarcinogenic properties , being one of the most active parts of the plant.
The use of Azadirachta indica (neem) for the treatment of dental ailments as gingivitis, plaque and periodontitis have been reported in India since several decades ago, mainly due to its antiseptic properties and activity
In a study of the subject, forty-five subjects with plaque-induced gingivitis divided into three groups were asked to rinse with 15 ml of mouthwash twice a day.
The study showed that Azadirachta indica (neem) was as effective in reducing periodontitis as Chlorhexidine, reducing significantly gingival bleeding and plaque indices in the non-placebo groups.
As with any other herbs and plants the use of Neem should follow your doctor's advice.
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